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Assessing the Effectiveness of Functional Genetic Screens for the Identification of Bioactive Metabolites

A common limitation for the identification of novel activities from functional (meta) genomic screens is the low number of active clones detected relative to the number of clones screened. Here we demonstrate that constructing libraries with strains known to produce bioactives can greatly enhance th...

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Detalles Bibliográficos
Autores principales:	Penesyan, Anahit, Ballestriero, Francesco, Daim, Malak, Kjelleberg, Staffan, Thomas, Torsten, Egan, Suhelen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564156/ https://www.ncbi.nlm.nih.gov/pubmed/23271424 http://dx.doi.org/10.3390/md11010040

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