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Altered nitric oxide production mediates matrix-specific PAK2 and NF-κB activation by flow

Shear stress generated by distinct blood flow patterns modulates endothelial cell phenotype to spatially restrict atherosclerotic plaque development. Signaling through p21-activated kinase (PAK) mediates several of the deleterious effects of shear stress, including enhanced NF-κB activation and proi...

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Detalles Bibliográficos
Autores principales:	Yurdagul, Arif, Chen, Jie, Funk, Steven Daniel, Albert, Patrick, Kevil, Christopher G., Orr, A. Wayne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564533/ https://www.ncbi.nlm.nih.gov/pubmed/23171552 http://dx.doi.org/10.1091/mbc.E12-07-0513

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