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Caenorhabditis elegans reveals a FxNPxY-independent low-density lipoprotein receptor internalization mechanism mediated by epsin1

Low-density lipoprotein receptor (LDLR) internalization clears cholesterol-laden LDL particles from circulation in humans. Defects in clathrin-dependent LDLR endocytosis promote elevated serum cholesterol levels and can lead to atherosclerosis. However, our understanding of the mechanisms that contr...

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Detalles Bibliográficos
Autores principales:	Kang, Yuan-Lin, Yochem, John, Bell, Leslie, Sorensen, Erika B., Chen, Lihsia, Conner, Sean D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564534/ https://www.ncbi.nlm.nih.gov/pubmed/23242996 http://dx.doi.org/10.1091/mbc.E12-02-0163

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