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Notch signaling from the endosome requires a conserved dileucine motif

Notch signaling is reliant on γ-secretase–mediated processing, although the subcellular location where γ-secretase cleaves Notch to initiate signaling remains unresolved. Accumulating evidence demonstrates that Notch signaling is modulated by endocytosis and endosomal transport. In this study, we in...

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Detalles Bibliográficos
Autores principales:	Zheng, Li, Saunders, Cosmo A., Sorensen, Erika B., Waxmonsky, Nicole C., Conner, Sean D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564540/ https://www.ncbi.nlm.nih.gov/pubmed/23171551 http://dx.doi.org/10.1091/mbc.E12-02-0081

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