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European cardiovascular magnetic resonance (EuroCMR) registry – multi national results from 57 centers in 15 countries

ABSTRACT: BACKGROUND: The EuroCMR registry sought to evaluate indications, image quality, safety and impact on patient management of clinical routine CMR in a multi-national European setting. Furthermore, interim analysis of the specific protocols should underscore the prognostic potential of CMR. M...

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Autores principales: Bruder, Oliver, Wagner, Anja, Lombardi, Massimo, Schwitter, Jürg, van Rossum, Albert, Pilz, Günter, Nothnagel, Detlev, Steen, Henning, Petersen, Steffen, Nagel, Eike, Prasad, Sanjay, Schumm, Julia, Greulich, Simon, Cagnolo, Alessandro, Monney, Pierre, Deluigi, Christina C, Dill, Thorsten, Frank, Herbert, Sabin, Georg, Schneider, Steffen, Mahrholdt, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564740/
https://www.ncbi.nlm.nih.gov/pubmed/23331632
http://dx.doi.org/10.1186/1532-429X-15-9
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author Bruder, Oliver
Wagner, Anja
Lombardi, Massimo
Schwitter, Jürg
van Rossum, Albert
Pilz, Günter
Nothnagel, Detlev
Steen, Henning
Petersen, Steffen
Nagel, Eike
Prasad, Sanjay
Schumm, Julia
Greulich, Simon
Cagnolo, Alessandro
Monney, Pierre
Deluigi, Christina C
Dill, Thorsten
Frank, Herbert
Sabin, Georg
Schneider, Steffen
Mahrholdt, Heiko
author_facet Bruder, Oliver
Wagner, Anja
Lombardi, Massimo
Schwitter, Jürg
van Rossum, Albert
Pilz, Günter
Nothnagel, Detlev
Steen, Henning
Petersen, Steffen
Nagel, Eike
Prasad, Sanjay
Schumm, Julia
Greulich, Simon
Cagnolo, Alessandro
Monney, Pierre
Deluigi, Christina C
Dill, Thorsten
Frank, Herbert
Sabin, Georg
Schneider, Steffen
Mahrholdt, Heiko
author_sort Bruder, Oliver
collection PubMed
description ABSTRACT: BACKGROUND: The EuroCMR registry sought to evaluate indications, image quality, safety and impact on patient management of clinical routine CMR in a multi-national European setting. Furthermore, interim analysis of the specific protocols should underscore the prognostic potential of CMR. METHODS: Multi-center registry with consecutive enrolment of patients in 57 centers in 15 countries. More than 27000 consecutive patients were enrolled. RESULTS: The most important indications were risk stratification in suspected CAD/Ischemia (34.2%), workup of myocarditis/cardiomyopathies (32.2%), as well as assessment of viability (14.6%). Image quality was diagnostic in more than 98% of cases. Severe complications occurred in 0.026%, always associated with stress testing. No patient died during or due to CMR. In 61.8% CMR findings impacted on patient management. Importantly, in nearly 8.7% the final diagnosis based on CMR was different to the diagnosis before CMR, leading to a complete change in management. Interim analysis of suspected CAD and risk stratification in HCM specific protocols revealed a low rate of adverse events for suspected CAD patients with normal stress CMR (1.0% per year), and for HCM patients without LGE (2.7% per year). CONCLUSION: The most important indications in Europe are risk stratification in suspected CAD/Ischemia, work-up of myocarditis and cardiomyopathies, as well as assessment of viability. CMR imaging is a safe procedure, has diagnostic image quality in more than 98% of cases, and its results have strong impact on patient management. Interim analyses of the specific protocols underscore the prognostic value of clinical routine CMR in CAD and HCM. CONDENSED ABSTRACT: The EuroCMR registry sought to evaluate indications, image quality, safety and impact on patient management of clinical routine CMR in a multi-national European setting in a large number of cases (n > 27000). Based on our data CMR is frequently performed in European daily clinical routine. The most important indications in Europe are risk stratification in suspected CAD/Ischemia, work-up of myocarditis and cardiomyopathies, as well as assessment of viability. CMR imaging is a safe procedure, has diagnostic image quality in more than 98% of cases, and its results have strong impact on patient management. Interim analyses of the specific protocols underscore the prognostic value of clinical routine CMR in CAD and HCM.
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spelling pubmed-35647402013-02-08 European cardiovascular magnetic resonance (EuroCMR) registry – multi national results from 57 centers in 15 countries Bruder, Oliver Wagner, Anja Lombardi, Massimo Schwitter, Jürg van Rossum, Albert Pilz, Günter Nothnagel, Detlev Steen, Henning Petersen, Steffen Nagel, Eike Prasad, Sanjay Schumm, Julia Greulich, Simon Cagnolo, Alessandro Monney, Pierre Deluigi, Christina C Dill, Thorsten Frank, Herbert Sabin, Georg Schneider, Steffen Mahrholdt, Heiko J Cardiovasc Magn Reson Research ABSTRACT: BACKGROUND: The EuroCMR registry sought to evaluate indications, image quality, safety and impact on patient management of clinical routine CMR in a multi-national European setting. Furthermore, interim analysis of the specific protocols should underscore the prognostic potential of CMR. METHODS: Multi-center registry with consecutive enrolment of patients in 57 centers in 15 countries. More than 27000 consecutive patients were enrolled. RESULTS: The most important indications were risk stratification in suspected CAD/Ischemia (34.2%), workup of myocarditis/cardiomyopathies (32.2%), as well as assessment of viability (14.6%). Image quality was diagnostic in more than 98% of cases. Severe complications occurred in 0.026%, always associated with stress testing. No patient died during or due to CMR. In 61.8% CMR findings impacted on patient management. Importantly, in nearly 8.7% the final diagnosis based on CMR was different to the diagnosis before CMR, leading to a complete change in management. Interim analysis of suspected CAD and risk stratification in HCM specific protocols revealed a low rate of adverse events for suspected CAD patients with normal stress CMR (1.0% per year), and for HCM patients without LGE (2.7% per year). CONCLUSION: The most important indications in Europe are risk stratification in suspected CAD/Ischemia, work-up of myocarditis and cardiomyopathies, as well as assessment of viability. CMR imaging is a safe procedure, has diagnostic image quality in more than 98% of cases, and its results have strong impact on patient management. Interim analyses of the specific protocols underscore the prognostic value of clinical routine CMR in CAD and HCM. CONDENSED ABSTRACT: The EuroCMR registry sought to evaluate indications, image quality, safety and impact on patient management of clinical routine CMR in a multi-national European setting in a large number of cases (n > 27000). Based on our data CMR is frequently performed in European daily clinical routine. The most important indications in Europe are risk stratification in suspected CAD/Ischemia, work-up of myocarditis and cardiomyopathies, as well as assessment of viability. CMR imaging is a safe procedure, has diagnostic image quality in more than 98% of cases, and its results have strong impact on patient management. Interim analyses of the specific protocols underscore the prognostic value of clinical routine CMR in CAD and HCM. BioMed Central 2013-01-18 /pmc/articles/PMC3564740/ /pubmed/23331632 http://dx.doi.org/10.1186/1532-429X-15-9 Text en Copyright ©2013 Bruder et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Bruder, Oliver
Wagner, Anja
Lombardi, Massimo
Schwitter, Jürg
van Rossum, Albert
Pilz, Günter
Nothnagel, Detlev
Steen, Henning
Petersen, Steffen
Nagel, Eike
Prasad, Sanjay
Schumm, Julia
Greulich, Simon
Cagnolo, Alessandro
Monney, Pierre
Deluigi, Christina C
Dill, Thorsten
Frank, Herbert
Sabin, Georg
Schneider, Steffen
Mahrholdt, Heiko
European cardiovascular magnetic resonance (EuroCMR) registry – multi national results from 57 centers in 15 countries
title European cardiovascular magnetic resonance (EuroCMR) registry – multi national results from 57 centers in 15 countries
title_full European cardiovascular magnetic resonance (EuroCMR) registry – multi national results from 57 centers in 15 countries
title_fullStr European cardiovascular magnetic resonance (EuroCMR) registry – multi national results from 57 centers in 15 countries
title_full_unstemmed European cardiovascular magnetic resonance (EuroCMR) registry – multi national results from 57 centers in 15 countries
title_short European cardiovascular magnetic resonance (EuroCMR) registry – multi national results from 57 centers in 15 countries
title_sort european cardiovascular magnetic resonance (eurocmr) registry – multi national results from 57 centers in 15 countries
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564740/
https://www.ncbi.nlm.nih.gov/pubmed/23331632
http://dx.doi.org/10.1186/1532-429X-15-9
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