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The Oncogenic Role of microRNA-130a/301a/454 in Human Colorectal Cancer via Targeting Smad4 Expression

Transforming growth factor (TGF)-β/Smad signaling plays an important role in colon cancer development, progression and metastasis. In this study we demonstrated that the microRNA-130a/301a/454 family is up-regulated in colon cancer tissues compared to paired adjacent normal mucosa, which share the s...

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Detalles Bibliográficos
Autores principales: Liu, Lin, Nie, Jing, Chen, Lin, Dong, Guanglong, Du, Xiaohui, Wu, Xin, Tang, Yun, Han, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564758/
https://www.ncbi.nlm.nih.gov/pubmed/23393589
http://dx.doi.org/10.1371/journal.pone.0055532