Human milk glycosaminoglycans: the state of the art and future perspectives

Recently, a complete characterization and detailed evaluation of the glycosaminoglycans of human milk were performed. The total glycosaminoglycans content in milk from healthy mothers having delivered term or preterm newborns showed a constant pattern which was essentially composed of two main polys...

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Autores principales: Coppa, Giovanni Valentino, Gabrielli, Orazio, Bertino, Enrico, Zampini, Lucia, Galeazzi, Tiziana, Padella, Lucia, Santoro, Lucia, Marchesiello, Rita Lucia, Galeotti, Fabio, Maccari, Francesca, Volpi, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564826/
https://www.ncbi.nlm.nih.gov/pubmed/23321150
http://dx.doi.org/10.1186/1824-7288-39-2
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author Coppa, Giovanni Valentino
Gabrielli, Orazio
Bertino, Enrico
Zampini, Lucia
Galeazzi, Tiziana
Padella, Lucia
Santoro, Lucia
Marchesiello, Rita Lucia
Galeotti, Fabio
Maccari, Francesca
Volpi, Nicola
author_facet Coppa, Giovanni Valentino
Gabrielli, Orazio
Bertino, Enrico
Zampini, Lucia
Galeazzi, Tiziana
Padella, Lucia
Santoro, Lucia
Marchesiello, Rita Lucia
Galeotti, Fabio
Maccari, Francesca
Volpi, Nicola
author_sort Coppa, Giovanni Valentino
collection PubMed
description Recently, a complete characterization and detailed evaluation of the glycosaminoglycans of human milk were performed. The total glycosaminoglycans content in milk from healthy mothers having delivered term or preterm newborns showed a constant pattern which was essentially composed of two main polysaccharides: chondroitin sulfate (60-70%) and heparin (30-40%). Moreover, considerable variations of glycosaminoglycans concentration were found during the first month of lactation, the highest values being present in colostrum compared to mature milk. Metabolism and potential biological functions of human milk glycosaminoglycans are hypothesized and future studies are encouraged.
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spelling pubmed-35648262013-02-08 Human milk glycosaminoglycans: the state of the art and future perspectives Coppa, Giovanni Valentino Gabrielli, Orazio Bertino, Enrico Zampini, Lucia Galeazzi, Tiziana Padella, Lucia Santoro, Lucia Marchesiello, Rita Lucia Galeotti, Fabio Maccari, Francesca Volpi, Nicola Ital J Pediatr Commentary Recently, a complete characterization and detailed evaluation of the glycosaminoglycans of human milk were performed. The total glycosaminoglycans content in milk from healthy mothers having delivered term or preterm newborns showed a constant pattern which was essentially composed of two main polysaccharides: chondroitin sulfate (60-70%) and heparin (30-40%). Moreover, considerable variations of glycosaminoglycans concentration were found during the first month of lactation, the highest values being present in colostrum compared to mature milk. Metabolism and potential biological functions of human milk glycosaminoglycans are hypothesized and future studies are encouraged. BioMed Central 2013-01-15 /pmc/articles/PMC3564826/ /pubmed/23321150 http://dx.doi.org/10.1186/1824-7288-39-2 Text en Copyright ©2013 Coppa et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Coppa, Giovanni Valentino
Gabrielli, Orazio
Bertino, Enrico
Zampini, Lucia
Galeazzi, Tiziana
Padella, Lucia
Santoro, Lucia
Marchesiello, Rita Lucia
Galeotti, Fabio
Maccari, Francesca
Volpi, Nicola
Human milk glycosaminoglycans: the state of the art and future perspectives
title Human milk glycosaminoglycans: the state of the art and future perspectives
title_full Human milk glycosaminoglycans: the state of the art and future perspectives
title_fullStr Human milk glycosaminoglycans: the state of the art and future perspectives
title_full_unstemmed Human milk glycosaminoglycans: the state of the art and future perspectives
title_short Human milk glycosaminoglycans: the state of the art and future perspectives
title_sort human milk glycosaminoglycans: the state of the art and future perspectives
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564826/
https://www.ncbi.nlm.nih.gov/pubmed/23321150
http://dx.doi.org/10.1186/1824-7288-39-2
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