Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variants

BACKGROUND: Breastfeeding is a leading cause of infant HIV-1 infection in the developing world, yet only a minority of infants exposed to HIV-1 via breastfeeding become infected. As a genetic bottleneck severely restricts the number of postnatally-transmitted variants, genetic or phenotypic properti...

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Detalles Bibliográficos
Autores principales: Fouda, Genevieve G, Mahlokozera, Tatenda, Salazar-Gonzalez, Jesus F, Salazar, Maria G, Learn, Gerald, Kumar, Surender B, Dennison, S Moses, Russell, Elizabeth, Rizzolo, Katherine, Jaeger, Frederick, Cai, Fangping, Vandergrift, Nathan A, Gao, Feng, Hahn, Beatrice, Shaw, George M, Ochsenbauer, Christina, Swanstrom, Ronald, Meshnick, Steve, Mwapasa, Victor, Kalilani, Linda, Fiscus, Susan, Montefiori, David, Haynes, Barton, Kwiek, Jesse, Alam, S Munir, Permar, Sallie R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564832/
https://www.ncbi.nlm.nih.gov/pubmed/23305422
http://dx.doi.org/10.1186/1742-4690-10-3

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