Cargando…
Integrated Genomic Analysis of the 8q24 Amplification in Endometrial Cancers Identifies ATAD2 as Essential to MYC-Dependent Cancers
Chromosome 8q24 is the most commonly amplified region across multiple cancer types, and the typical length of the amplification suggests that it may target additional genes to MYC. To explore the roles of the genes most frequently included in 8q24 amplifications, we analyzed the relation between cop...
Autores principales: | Raeder, Maria B., Birkeland, Even, Trovik, Jone, Krakstad, Camilla, Shehata, Shyemaa, Schumacher, Steven, Zack, Travis I., Krohn, Antje, Werner, Henrica MJ., Moody, Susan E., Wik, Elisabeth, Stefansson, Ingunn M., Holst, Frederik, Oyan, Anne M., Tamayo, Pablo, Mesirov, Jill P., Kalland, Karl H., Akslen, Lars A., Simon, Ronald, Beroukhim, Rameen, Salvesen, Helga B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564856/ https://www.ncbi.nlm.nih.gov/pubmed/23393560 http://dx.doi.org/10.1371/journal.pone.0054873 |
Ejemplares similares
-
ATAD2 overexpression links to enrichment of B-MYB-translational signatures and development of aggressive endometrial carcinoma
por: Krakstad, Camilla, et al.
Publicado: (2015) -
Tumor necrosis is an important hallmark of aggressive endometrial cancer and associates with hypoxia, angiogenesis and inflammation responses
por: Bredholt, Geir, et al.
Publicado: (2015) -
Loss of GPER identifies new targets for therapy among a subgroup of ERα-positive endometrial cancer patients with poor outcome
por: Krakstad, C, et al.
Publicado: (2012) -
Increased angiogenesis is associated with a 32-gene expression signature and 6p21 amplification in aggressive endometrial cancer
por: Stefansson, Ingunn M., et al.
Publicado: (2015) -
Aneuploidy related transcriptional changes in endometrial cancer link low expression of chromosome 15q genes to poor survival
por: Mauland, Karen Klepsland, et al.
Publicado: (2016)