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Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kγ in the MDA-MB-231 metastatic breast cancer cell line

BACKGROUND: Cancer cell migration is fundamentally required for breast tumour invasion and metastasis. The insulin-like growth factor 1 tyrosine kinase receptor (IGF-1R) and the chemokine G-protein coupled receptor, CXCR4 have been shown to play an important role in breast cancer metastasis. Our pre...

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Detalles Bibliográficos
Autores principales: Niu, Meizhi, Klingler-Hoffmann, Manuela, Brazzatti, Julie A, Forbes, Briony, Akekawatchai, Chareeporn, Hoffmann, Peter, McColl, Shaun R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564858/
https://www.ncbi.nlm.nih.gov/pubmed/23320409
http://dx.doi.org/10.1186/1477-5956-11-4

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