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Chotosan ameliorates cognitive and emotional deficits in an animal model of type 2 diabetes: possible involvement of cholinergic and VEGF/PDGF mechanisms in the brain
BACKGROUND: Diabetes is one of the risk factors for cognitive deficits such as Alzheimer’s disease. To obtain a better understanding of the anti-dementia effect of chotosan (CTS), a Kampo formula, we investigated its effects on cognitive and emotional deficits of type 2 diabetic db/db mice and putat...
Autores principales: | Zhao, Qi, Niu, Yimin, Matsumoto, Kinzo, Tsuneyama, Koichi, Tanaka, Ken, Miyata, Takeshi, Yokozawa, Takako |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564934/ https://www.ncbi.nlm.nih.gov/pubmed/23082896 http://dx.doi.org/10.1186/1472-6882-12-188 |
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