Cargando…

In-vitro characterization of novel and functional regulatory SNPs in the promoter region of IL2 and IL2R alpha in a Gabonese population

BACKGROUND: The selection pressure imposed by the parasite has a functional consequence on the immune genes, leading to altered immune function in which regulatory T cells (Tregs) induced by parasites during infectious challenges modulate or thwart T effector cell mechanism. METHODS: We identified a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Xiangsheng, Kühne, Vera, Kun, Jürgen F J, Soboslay, Peter T, Lell, Bertrand, TP, Velavan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564939/ https://www.ncbi.nlm.nih.gov/pubmed/23217119 http://dx.doi.org/10.1186/1471-2350-13-117

Ejemplares similares

Artesunate – amodiaquine combination therapy for falciparum malaria in young Gabonese children
por: Oyakhirome, Sunny, et al.
Publicado: (2007)

Parasite-Specific IL-17-Type Cytokine Responses and Soluble IL-17 Receptor Levels in Alveolar Echinococcosis Patients
por: Lechner, Christian J., et al.
Publicado: (2012)

Impact of Helminth Infections during Pregnancy on Vaccine Immunogenicity in Gabonese Infants
por: Flügge, Judith, et al.
Publicado: (2020)

Causes of fever in Gabonese children: a cross-sectional hospital-based study
por: Fernandes, José Francisco, et al.
Publicado: (2020)

High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children
por: Mombo-Ngoma, Ghyslain, et al.
Publicado: (2011)

Antipyretic effect of ibuprofen in Gabonese children with uncomplicated falciparum malaria: a randomized, double-blind, placebo-controlled trial
por: Matsiégui, Pierre-Blaise, et al.
Publicado: (2008)

Data on Gabonese rodents and their Plasmodium
por: Boundenga, Larson, et al.
Publicado: (2019)

Cellular and antibody response in GMZ2-vaccinated Gabonese volunteers in a controlled human malaria infection trial
por: Nouatin, Odilon, et al.
Publicado: (2022)

Self-Reactivities to the Non-Erythroid Alpha Spectrin Correlate with Cerebral Malaria in Gabonese Children
por: Guiyedi, Vincent, et al.
Publicado: (2007)

IL-2 coordinates IL-2–producing and regulatory T cell interplay
por: Amado, Inês F., et al.
Publicado: (2013)

Investigating antibiotic resistance in enterococci in Gabonese livestock
por: Desire, Otsaghe Ekore, et al.
Publicado: (2022)

Regulatory T Cells and Parasites
por: Velavan, TP., et al.
Publicado: (2011)

Association Analysis of IL10, TNF-α, and IL23R-IL12RB2 SNPs with Behçet’s Disease Risk in Western Algeria
por: Khaib Dit Naib, Ouahiba, et al.
Publicado: (2013)

Molecular surveillance and genetic divergence of rotavirus A antigenic epitopes in Gabonese children with acute gastroenteritis
por: Manouana, Gédéon Prince, et al.
Publicado: (2021)

Co-infection of human parvovirus B19 with Plasmodium falciparum contributes to malaria disease severity in Gabonese patients
por: Toan, Nguyen L, et al.
Publicado: (2013)

Acute dengue virus 2 infection in Gabonese patients is associated with an early innate immune response, including strong interferon alpha production
por: Becquart, Pierre, et al.
Publicado: (2010)

Soluble IL-2 alpha and ovarian cancer.
por: Barton, D. P.
Publicado: (1994)

Combination of FLG mutations and SNPs of IL-17A and IL-19 influence on atopic dermatitis occurrence
por: Klonowska, Jolanta, et al.
Publicado: (2021)

The distribution of SNPs in human gene regulatory regions
por: Guo, Yongjian, et al.
Publicado: (2005)

Functional Modulation of Regulatory T Cells by IL-2
por: Moon, Byung-In, et al.
Publicado: (2015)

Severe falciparum malaria in Gabonese children: clinical and laboratory features
por: Dzeing-Ella, Arnaud, et al.
Publicado: (2005)

Prevalence of Plasmodium falciparum infection in asymptomatic rural Gabonese populations
por: Nkoghe, Dieudonné, et al.
Publicado: (2011)

Association between single nucleotide polymorphisms (SNPs) of IL1, IL12, IL28 and TLR4 and symptoms of congenital cytomegalovirus infection
por: Jedlińska-Pijanowska, Dominika, et al.
Publicado: (2020)

Circulating IL-6, IL-10, and TNF-alpha and IL-10/IL-6 and IL-10/TNF-alpha ratio profiles of polyparasitized individuals in rural and urban areas of gabon
por: M’Bondoukwé, Noé Patrick, et al.
Publicado: (2022)

Levels of serum IL-1beta, IL-2, IL-8 and tumor necrosis factor-alpha in patients with unstable angina pectoris.
por: Ozeren, Ali, et al.
Publicado: (2003)

IL-2 and IL-15 dependent thymic development of Foxp3-expressing regulatory T lymphocytes
por: Apert, Cécile, et al.
Publicado: (2017)

IL‐1RL1a serum levels and IL1RL1 SNPs in the prediction of food allergy
por: Ketelaar, Maria E., et al.
Publicado: (2021)

Serum IL-1beta, sIL-2R, IL-6, IL-8 and TNF-alpha in schizophrenic patients, relation with symptomatology and responsiveness to risperidone treatment.
por: Erbağci, A B, et al.
Publicado: (2001)

IL-2 immunotherapy for targeting regulatory T cells in autoimmunity
por: Lykhopiy, Valentina, et al.
Publicado: (2023)

Antidiabetic potential of two medicinal plants used in Gabonese folk medicine
por: Agnaniet, Huguette, et al.
Publicado: (2016)

P03-010 - IL10 SNPs associated with BD in Western Algeria
por: Khaib Dit Naib, O, et al.
Publicado: (2013)

Bioinformatics Analysis of SNPs in IL-6 Gene Promoter of Jinghai Yellow Chickens
por: Xin, Shijie, et al.
Publicado: (2018)

The Interleukin-1 (IL-1) Superfamily Cytokines and Their Single Nucleotide Polymorphisms (SNPs)
por: Behzadi, Payam, et al.
Publicado: (2022)

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
por: Seddiki, Nabila, et al.
Publicado: (2006)

IL-15 Fosters Age-Driven Regulatory T Cell Accrual in the Face of Declining IL-2 Levels
por: Raynor, Jana, et al.
Publicado: (2013)

Induction of Plasmodium falciparum-Specific CD4(+) T Cells and Memory B Cells in Gabonese Children Vaccinated with RTS,S/AS01(E) and RTS,S/AS02(D)
por: Agnandji, Selidji T., et al.
Publicado: (2011)

“Too Big To Ignore”: A feasibility analysis of detecting fishing events in Gabonese small-scale fisheries
por: Cardiec, Floriane, et al.
Publicado: (2020)

Genetic diversity of the human immunodeficiency virus of type 1 in Gabonese transfusional settings
por: Mangala, Christian, et al.
Publicado: (2023)

An essential role for IL-2 receptor in regulatory T cell function
por: Chinen, Takatoshi, et al.
Publicado: (2016)

Cancer immunotherapy with T-cell targeting cytokines: IL-2 and IL-7
por: Kim, Ji-Hae, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_alte6pvsio5sj6agv0037ajtu7