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Phosphoglycerate dehydrogenase induces glioma cells proliferation and invasion by stabilizing forkhead box M1

Phosphoglycerate dehydrogenase (PHGDH) is the first enzyme branching from glycolysis in the three-step serine biosynthetic pathway. Recent evidence has shown that PHGDH is amplified in human breast cancer and melanoma and plays a key role in cancer metabolism. However, PHGDH expression in glioma and...

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Detalles Bibliográficos
Autores principales:	Liu, Jinlong, Guo, Shaolei, Li, Qingzhi, Yang, Lixuan, Xia, Zhibai, Zhang, Longjuan, Huang, Zhengsong, Zhang, Nu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2012
Materias:	Laboratory Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565087/ https://www.ncbi.nlm.nih.gov/pubmed/23229761 http://dx.doi.org/10.1007/s11060-012-1018-x

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