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An optical assay of the transport activity of ClC-7

Osteoporosis, characterized by excessive osteoclast mediated bone resorption, affects millions of people worldwide representing a major public health problem. ClC-7 is a chloride-proton exchanger localized in lysosomes and in the resorption lacuna in osteoclasts where it is essential for bone resorp...

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Detalles Bibliográficos
Autores principales: Zanardi, Ilaria, Zifarelli, Giovanni, Pusch, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565172/
https://www.ncbi.nlm.nih.gov/pubmed/23390581
http://dx.doi.org/10.1038/srep01231