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An optical assay of the transport activity of ClC-7
Osteoporosis, characterized by excessive osteoclast mediated bone resorption, affects millions of people worldwide representing a major public health problem. ClC-7 is a chloride-proton exchanger localized in lysosomes and in the resorption lacuna in osteoclasts where it is essential for bone resorp...
Autores principales: | Zanardi, Ilaria, Zifarelli, Giovanni, Pusch, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565172/ https://www.ncbi.nlm.nih.gov/pubmed/23390581 http://dx.doi.org/10.1038/srep01231 |
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