Evidence for sustained elevation of IL-6 in the CNS as a key contributor of depressive-like phenotypes

There is compelling clinical literature implicating a role for cytokines in the pathophysiology of major depressive disorder (MDD). Interleukin-6 (IL-6) and interleukin-1β (IL-1β) are pleiotropic inflammatory cytokines that have been reported to be elevated in patients with MDD. The present studies...

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Detalles Bibliográficos
Autores principales: Sukoff Rizzo, S J, Neal, S J, Hughes, Z A, Beyna, M, Rosenzweig-Lipson, S, Moss, S J, Brandon, N J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565187/
https://www.ncbi.nlm.nih.gov/pubmed/23212583
http://dx.doi.org/10.1038/tp.2012.120

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