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Antitumor Effects of Rapamycin in Pancreatic Cancer Cells by Inducing Apoptosis and Autophagy
Rapamycin (Rapa), an inhibitor of mammalian target of Rapamycin (mTOR), is an immunosuppressive agent that has anti-proliferative effects on some tumors. This study aims to investigate the effects of Rapa suppressing proliferation of pancreatic carcinoma PC-2 cells in vitro and its molecular mechani...
Autores principales: | Dai, Zhi-Jun, Gao, Jie, Ma, Xiao-Bin, Kang, Hua-Feng, Wang, Bao-Feng, Lu, Wang-Feng, Lin, Shuai, Wang, Xi-Jing, Wu, Wen-Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565263/ https://www.ncbi.nlm.nih.gov/pubmed/23344033 http://dx.doi.org/10.3390/ijms14010273 |
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