Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties

Polymer supported dichlorophosphate (PEG-OPOCl(2)) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized com...

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Detalles Bibliográficos
Autores principales: Naidu, Kalla Reddi Mohan, Khalivulla, Shaik Ibrahim, Rasheed, Syed, Fakurazi, Sharida, Arulselvan, Palanisamy, Lasekan, Ola, Abas, Faridah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565351/
https://www.ncbi.nlm.nih.gov/pubmed/23325050
http://dx.doi.org/10.3390/ijms14011843
Descripción
Sumario:Polymer supported dichlorophosphate (PEG-OPOCl(2)) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compounds and their anti-cancer activity are evaluated.

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