Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties

Polymer supported dichlorophosphate (PEG-OPOCl(2)) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized com...

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Autores principales: Naidu, Kalla Reddi Mohan, Khalivulla, Shaik Ibrahim, Rasheed, Syed, Fakurazi, Sharida, Arulselvan, Palanisamy, Lasekan, Ola, Abas, Faridah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565351/
https://www.ncbi.nlm.nih.gov/pubmed/23325050
http://dx.doi.org/10.3390/ijms14011843
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author Naidu, Kalla Reddi Mohan
Khalivulla, Shaik Ibrahim
Rasheed, Syed
Fakurazi, Sharida
Arulselvan, Palanisamy
Lasekan, Ola
Abas, Faridah
author_facet Naidu, Kalla Reddi Mohan
Khalivulla, Shaik Ibrahim
Rasheed, Syed
Fakurazi, Sharida
Arulselvan, Palanisamy
Lasekan, Ola
Abas, Faridah
author_sort Naidu, Kalla Reddi Mohan
collection PubMed
description Polymer supported dichlorophosphate (PEG-OPOCl(2)) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compounds and their anti-cancer activity are evaluated.
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spelling pubmed-35653512013-03-13 Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties Naidu, Kalla Reddi Mohan Khalivulla, Shaik Ibrahim Rasheed, Syed Fakurazi, Sharida Arulselvan, Palanisamy Lasekan, Ola Abas, Faridah Int J Mol Sci Article Polymer supported dichlorophosphate (PEG-OPOCl(2)) is an efficient green catalyst for the electrophilic substitution reaction of indole with aromatic aldehydes, in neat condition, to afford an excellent yield of bis(indolyl) methanes with short reaction time, at room temperature. The synthesized compounds and their anti-cancer activity are evaluated. MDPI 2013-01-16 /pmc/articles/PMC3565351/ /pubmed/23325050 http://dx.doi.org/10.3390/ijms14011843 Text en © 2013 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Naidu, Kalla Reddi Mohan
Khalivulla, Shaik Ibrahim
Rasheed, Syed
Fakurazi, Sharida
Arulselvan, Palanisamy
Lasekan, Ola
Abas, Faridah
Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties
title Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties
title_full Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties
title_fullStr Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties
title_full_unstemmed Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties
title_short Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties
title_sort synthesis of bisindolylmethanes and their cytotoxicity properties
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565351/
https://www.ncbi.nlm.nih.gov/pubmed/23325050
http://dx.doi.org/10.3390/ijms14011843
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