In vivo knockdown of GAD67 in the amygdala disrupts fear extinction and the anxiolytic-like effect of diazepam in mice

In mammals, γ-aminobutyric acid (GABA) transmission in the amygdala is particularly important for controlling levels of fear and anxiety. Most GABA synthesis in the brain is catalyzed in inhibitory neurons from ℒ-glutamic acid by the enzyme glutamic acid decarboxylase 67 (GAD67). In the current stud...

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Detalles Bibliográficos
Autores principales: Heldt, S A, Mou, L, Ressler, K J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565763/
https://www.ncbi.nlm.nih.gov/pubmed/23149445
http://dx.doi.org/10.1038/tp.2012.101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565763/
https://www.ncbi.nlm.nih.gov/pubmed/23149445
http://dx.doi.org/10.1038/tp.2012.101

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