Cargando…

Convergent animal and human evidence suggests the activin/inhibin pathway to be involved in antidepressant response

Despite the overt need for improved treatment modalities in depression, efforts to develop conceptually novel antidepressants have been relatively unsuccessful so far. Here we present a translational approach combining results from hypothesis-free animal experiments with data from a genetic associat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ganea, K, Menke, A, Schmidt, M V, Lucae, S, Rammes, G, Liebl, C, Harbich, D, Sterlemann, V, Storch, C, Uhr, M, Holsboer, F, Binder, E B, Sillaber, I, Müller, M B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565812/ https://www.ncbi.nlm.nih.gov/pubmed/23092981 http://dx.doi.org/10.1038/tp.2012.104

Ejemplares similares

RNA expression profiling in depressed patients suggests retinoid-related orphan receptor alpha as a biomarker for antidepressant response
por: Hennings, J M, et al.
Publicado: (2015)

Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity
por: Carrillo-Roa, Tania, et al.
Publicado: (2017)

Variations in activin receptor, inhibin/activin subunit and follistatin mRNAs in human prostate tumour tissues
por: Schaik, R H N van, et al.
Publicado: (2000)

Prognostic impact of activin subunit inhibin beta A in gastric and esophageal adenocarcinomas
por: Staudacher, J. J., et al.
Publicado: (2022)

Inactivating the Uninhibited: The Tale of Activins and Inhibins in Pulmonary Arterial Hypertension
por: Ryanto, Gusty Rizky Teguh, et al.
Publicado: (2023)

Immunolocalization of activin and inhibin at different stages of follicular development in the lizard Sceloporus torquatus
por: Cruz-Cano, N.B., et al.
Publicado: (2023)

Purine and pyrimidine metabolism: Convergent evidence on chronic antidepressant treatment response in mice and humans
por: Park, Dong Ik, et al.
Publicado: (2016)

Genetic analysis of activin/inhibin β subunits in zebrafish development and reproduction
por: Zhao, Cheng, et al.
Publicado: (2022)

The glycoprotein-hormones activin A and inhibin A interfere with dendritic cell maturation
por: Segerer, Sabine E, et al.
Publicado: (2008)

FKBP5 Gene Expression Predicts Antidepressant Treatment Outcome in Depression
por: Ising, Marcus, et al.
Publicado: (2019)

IGSF1 Does Not Regulate Spermatogenesis or Modify FSH Synthesis in Response to Inhibins or Activins
por: Brûlé, Emilie, et al.
Publicado: (2021)

Immunohistochemical localization of inhibin/activin subunits in adult Asian elephant (Elephas maximus) testes
por: CHAICHANATHONG, Sirinart, et al.
Publicado: (2018)

Metabolite profiling of antidepressant drug action reveals novel drug targets beyond monoamine elevation
por: Webhofer, C, et al.
Publicado: (2011)

Recurrent suicide attempts affect normalization of HPA axis dysregulation after recovery from major depression
por: Hennings, Johannes M., et al.
Publicado: (2022)

Role of inhibin and activin in the modulation of gonadotropin- and steroid-induced oocyte maturation in the teleost Fundulus heteroclitus
por: Petrino, Teresa R, et al.
Publicado: (2007)

Inhibin/activin expression in human and rodent liver: subunits α and βB as new players in human hepatocellular carcinoma?
por: Frost, K, et al.
Publicado: (2011)

Inhibin removes the inhibitory effects of activin on steroid enzyme expression and androgen production by normal ovarian thecal cells
por: Young, J M, et al.
Publicado: (2012)

Effects of Pharmacokinetic Gene Variation on Therapeutic Drug Levels and Antidepressant Treatment Response
por: Scherf-Clavel, Maike, et al.
Publicado: (2022)

Plasma fibrinogen: now also an antidepressant response marker?
por: Martins-de-Souza, D, et al.
Publicado: (2014)

Human testicular germ cell tumours express inhibin subunits, activin receptors and follistatin mRNAs.
por: van Schaik, R. H., et al.
Publicado: (1997)

Evidence of inhibin/activin subunit betaC and betaE synthesis in normal human endometrial tissue
por: Mylonas, Ioannis, et al.
Publicado: (2010)

Seasonal Changes in Immunoreactivity of Inhibin/Activin Subunits in the Epididymis of Wild Ground Squirrels (Citellus dauricus Brandt)
por: ZHANG, Mengyuan, et al.
Publicado: (2013)

circRNA-Mediated Inhibin–Activin Balance Regulation in Ovarian Granulosa Cell Apoptosis and Follicular Atresia
por: Ma, Mengnan, et al.
Publicado: (2021)

Maternal Serum Activin A, Inhibin A and Follistatin-Related Proteins across Preeclampsia: Insights into Their Role in Pathogenesis and Prediction
por: Barrero, Jorge A., et al.
Publicado: (2023)

Correction: Evidence of inhibin/activin subunit betaC and betaE synthesis in normal human endometrial tissue
por: Mylonas, Ioannis, et al.
Publicado: (2011)

SUN-244 Role of Activin, Follistatin, and Inhibin in the Regulation of KISS-1 Gene Expression in Hypothalamic Cell Models
por: Oride, Aki, et al.
Publicado: (2020)

Dentate gyrus activin signaling mediates the antidepressant response
por: Gergues, Mark M., et al.
Publicado: (2021)

The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders
por: Thoeringer, C. K., et al.
Publicado: (2008)

Delineation of molecular pathway activities of the chronic antidepressant treatment response suggests important roles for glutamatergic and ubiquitin–proteasome systems
por: Park, D I, et al.
Publicado: (2017)

Maternal Circulating Levels of Activin A, Inhibin A, sFlt-1 and Endoglin at Parturition in Normal Pregnancy and Pre-Eclampsia
por: Reddy, Aparna, et al.
Publicado: (2009)

Epigenetic alterations in depression and antidepressant treatment
por: Menke, Andreas, et al.
Publicado: (2014)

Association of FKBP51 with Priming of Autophagy Pathways and Mediation of Antidepressant Treatment Response: Evidence in Cells, Mice, and Humans
por: Gassen, Nils C., et al.
Publicado: (2014)

Proteomic Differences in Blood Plasma Associated with Antidepressant Treatment Response
por: Turck, Christoph W., et al.
Publicado: (2017)

Roles of intracerebral activin, inhibin, and follistatin in the regulation of Kiss-1 gene expression: Studies using primary cultures of fetal rat neuronal cells()
por: Tumurgan, Zolzaya, et al.
Publicado: (2020)

Serum Inhibin A and Inhibin B Levels in Epithelial Ovarian Cancer Patients
por: Walentowicz, Pawel, et al.
Publicado: (2014)

Redesigning antidepressant drug discovery
por: Holsboer, Florian
Publicado: (2014)

Inhibin as a marker for ovarian cancer.
por: Cooke, I., et al.
Publicado: (1995)

Weight-gain independent effect of mirtazapine on fasting plasma lipids in healthy men
por: Lechner, Katharina, et al.
Publicado: (2023)

Proliferation rates and gene expression profiles in human lymphoblastoid cell lines from patients with depression characterized in response to antidepressant drug therapy
por: Breitfeld, J, et al.
Publicado: (2016)

Possible Associations of NTRK2 Polymorphisms with Antidepressant Treatment Outcome: Findings from an Extended Tag SNP Approach
por: Hennings, Johannes M., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_4ge820ior9env41nalgh7gji42