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A Novel Selective LSD1/KDM1A Inhibitor Epigenetically Blocks Herpes Simplex Virus Lytic Replication and Reactivation from Latency

Cellular processes requiring access to the DNA genome are regulated by an overlay of epigenetic modifications, including histone modification and chromatin remodeling. Similar to the cellular host, many nuclear DNA viruses that depend upon the host cell’s transcriptional machinery are also subject t...

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Detalles Bibliográficos
Autores principales:	Liang, Yu, Quenelle, Debra, Vogel, Jodi L., Mascaro, Cristina, Ortega, Alberto, Kristie, Thomas M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565832/ https://www.ncbi.nlm.nih.gov/pubmed/23386436 http://dx.doi.org/10.1128/mBio.00558-12

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