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Rational Engineering of a Human Anti-Dengue Antibody through Experimentally Validated Computational Docking

Antibodies play an increasing pivotal role in both basic research and the biopharmaceutical sector, therefore technology for characterizing and improving their properties through rational engineering is desirable. This is a difficult task thought to require high-resolution x-ray structures, which ar...

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Detalles Bibliográficos
Autores principales:	Simonelli, Luca, Pedotti, Mattia, Beltramello, Martina, Livoti, Elsa, Calzolai, Luigi, Sallusto, Federica, Lanzavecchia, Antonio, Varani, Luca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566030/ https://www.ncbi.nlm.nih.gov/pubmed/23405171 http://dx.doi.org/10.1371/journal.pone.0055561

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