The Level of Ets-1 Protein Is Regulated by Poly(ADP-Ribose) Polymerase-1 (PARP-1) in Cancer Cells to Prevent DNA Damage

Ets-1 is a transcription factor that regulates many genes involved in cancer progression and in tumour invasion. It is a poor prognostic marker for breast, lung, colorectal and ovary carcinomas. Here, we identified poly(ADP-ribose) polymerase-1 (PARP-1) as a novel interaction partner of Ets-1. We sh...

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Detalles Bibliográficos
Autores principales: Legrand, Arnaud J., Choul-Li, Souhaila, Spriet, Corentin, Idziorek, Thierry, Vicogne, Dorothée, Drobecq, Hervé, Dantzer, Françoise, Villeret, Vincent, Aumercier, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566071/
https://www.ncbi.nlm.nih.gov/pubmed/23405229
http://dx.doi.org/10.1371/journal.pone.0055883

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