Tempol Moderately Extends Survival in a hSOD1(G93A) ALS Rat Model by Inhibiting Neuronal Cell Loss, Oxidative Damage and Levels of Non-Native hSOD1(G93A) Forms

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive dysfunction and death of motor neurons by mechanisms that remain unclear. Evidence indicates that oxidative mechanisms contribute to ALS pathology, but classical antioxidants have not performed...

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Detalles Bibliográficos
Autores principales: Linares, Edlaine, Seixas, Luciana V., dos Prazeres, Janaina N., Ladd, Fernando V. L., Ladd, Aliny A. B. L., Coppi, Antonio A., Augusto, Ohara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566093/
https://www.ncbi.nlm.nih.gov/pubmed/23405225
http://dx.doi.org/10.1371/journal.pone.0055868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566093/
https://www.ncbi.nlm.nih.gov/pubmed/23405225
http://dx.doi.org/10.1371/journal.pone.0055868

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