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Influence of the Presence of Tissue Expanders on Energy Deposition for Post-Mastectomy Radiotherapy
An increasing number of studies have shown that post-mastectomy radiotherapy presents benefits associated with the patients survival and a significant fraction of the treated patients makes use of tissue expanders for breast reconstruction. Some models of tissue expanders have a magnetic disk on the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566153/ https://www.ncbi.nlm.nih.gov/pubmed/23405149 http://dx.doi.org/10.1371/journal.pone.0055430 |
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author | Trombetta, Débora M. Cardoso, Simone C. Facure, Alessandro da Silva, Ademir X. da Rosa, Luiz Antonio R. |
author_facet | Trombetta, Débora M. Cardoso, Simone C. Facure, Alessandro da Silva, Ademir X. da Rosa, Luiz Antonio R. |
author_sort | Trombetta, Débora M. |
collection | PubMed |
description | An increasing number of studies have shown that post-mastectomy radiotherapy presents benefits associated with the patients survival and a significant fraction of the treated patients makes use of tissue expanders for breast reconstruction. Some models of tissue expanders have a magnetic disk on their surface that constitutes heterogeneity in the radiation field, which can affect the dose distribution during the radiotherapy treatment. In this study, the influence of a metallic heterogeneity positioned in a breast tissue expander was evaluated by means of Monte Carlo simulations using the MCNPX code and using Eclipse treatment planning system. Deposited energy values were calculated in structures which have clinical importance for the treatment. Additionally, the effect in the absorbed energy due to backscattering and attenuation of the incident beam caused by the heterogeneity, as well as due to the expansion of the prosthesis, was evaluated in target structures for a 6 MV photon beam by simulations. The dose distributions for a breast treatment were calculated using a convolution/superposition algorithm from the Eclipse treatment planning system. When compared with the smallest breast expander volume, underdosage of 7% was found for the largest volume of breast implant, in the case of frontal irradiation of the chest wall, by Monte Carlo simulations. No significant changes were found in dose distributions for the presence of the heterogeneity during the treatment planning of irradiation with an opposed pair of beams. Even considering the limitation of the treatment planning system, the results obtained with its use confirm those ones found by Monte Carlo simulations for a tangent beam irradiation. The presence of a heterogeneity didńt alters the dose distributions on treatment structures. The underdosage of 7% observed with Monte Carlo simulations were found for irradiation at 0°, not used frequently in a clinical routine. |
format | Online Article Text |
id | pubmed-3566153 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-35661532013-02-12 Influence of the Presence of Tissue Expanders on Energy Deposition for Post-Mastectomy Radiotherapy Trombetta, Débora M. Cardoso, Simone C. Facure, Alessandro da Silva, Ademir X. da Rosa, Luiz Antonio R. PLoS One Research Article An increasing number of studies have shown that post-mastectomy radiotherapy presents benefits associated with the patients survival and a significant fraction of the treated patients makes use of tissue expanders for breast reconstruction. Some models of tissue expanders have a magnetic disk on their surface that constitutes heterogeneity in the radiation field, which can affect the dose distribution during the radiotherapy treatment. In this study, the influence of a metallic heterogeneity positioned in a breast tissue expander was evaluated by means of Monte Carlo simulations using the MCNPX code and using Eclipse treatment planning system. Deposited energy values were calculated in structures which have clinical importance for the treatment. Additionally, the effect in the absorbed energy due to backscattering and attenuation of the incident beam caused by the heterogeneity, as well as due to the expansion of the prosthesis, was evaluated in target structures for a 6 MV photon beam by simulations. The dose distributions for a breast treatment were calculated using a convolution/superposition algorithm from the Eclipse treatment planning system. When compared with the smallest breast expander volume, underdosage of 7% was found for the largest volume of breast implant, in the case of frontal irradiation of the chest wall, by Monte Carlo simulations. No significant changes were found in dose distributions for the presence of the heterogeneity during the treatment planning of irradiation with an opposed pair of beams. Even considering the limitation of the treatment planning system, the results obtained with its use confirm those ones found by Monte Carlo simulations for a tangent beam irradiation. The presence of a heterogeneity didńt alters the dose distributions on treatment structures. The underdosage of 7% observed with Monte Carlo simulations were found for irradiation at 0°, not used frequently in a clinical routine. Public Library of Science 2013-02-06 /pmc/articles/PMC3566153/ /pubmed/23405149 http://dx.doi.org/10.1371/journal.pone.0055430 Text en © 2013 Trombetta et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Trombetta, Débora M. Cardoso, Simone C. Facure, Alessandro da Silva, Ademir X. da Rosa, Luiz Antonio R. Influence of the Presence of Tissue Expanders on Energy Deposition for Post-Mastectomy Radiotherapy |
title | Influence of the Presence of Tissue Expanders on Energy Deposition for Post-Mastectomy Radiotherapy |
title_full | Influence of the Presence of Tissue Expanders on Energy Deposition for Post-Mastectomy Radiotherapy |
title_fullStr | Influence of the Presence of Tissue Expanders on Energy Deposition for Post-Mastectomy Radiotherapy |
title_full_unstemmed | Influence of the Presence of Tissue Expanders on Energy Deposition for Post-Mastectomy Radiotherapy |
title_short | Influence of the Presence of Tissue Expanders on Energy Deposition for Post-Mastectomy Radiotherapy |
title_sort | influence of the presence of tissue expanders on energy deposition for post-mastectomy radiotherapy |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566153/ https://www.ncbi.nlm.nih.gov/pubmed/23405149 http://dx.doi.org/10.1371/journal.pone.0055430 |
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