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Long-Term Treatment of Thalidomide Ameliorates Amyloid-Like Pathology through Inhibition of β-Secretase in a Mouse Model of Alzheimer’s Disease

Thalidomide is a tumor necrosis factor alpha (TNFα) inhibitor which has been found to have abilities against tumor growth, angiogenesis and inflammation. Recently, it has been applied in clinic for the treatment of multiple myeloma as well as some inflammatory diseases. However, whether thalidomide...

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Detalles Bibliográficos
Autores principales: He, Ping, Cheng, Xin, Staufenbiel, Matthias, Li, Rena, Shen, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566218/
https://www.ncbi.nlm.nih.gov/pubmed/23405115
http://dx.doi.org/10.1371/journal.pone.0055091

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