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DNA Sequence Preferences of Transcriptional Activators Correlate More Strongly than Repressors with Nucleosomes

Transcription factors (TFs) and histone octamers are two abundant classes of DNA binding proteins that coordinate the transcriptional program in cells. Detailed studies of individual TFs have shown that TFs bind to nucleosome-occluded DNA sequences and induce nucleosome disruption/repositioning, whi...

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Detalles Bibliográficos
Autores principales:	Charoensawan, Varodom, Janga, Sarath Chandra, Bulyk, Martha L., Babu, M. Madan, Teichmann, Sarah A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566590/ https://www.ncbi.nlm.nih.gov/pubmed/22841002 http://dx.doi.org/10.1016/j.molcel.2012.06.028

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