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Extracting insights from the shape of complex data using topology
This paper applies topological methods to study complex high dimensional data sets by extracting shapes (patterns) and obtaining insights about them. Our method combines the best features of existing standard methodologies such as principal component and cluster analyses to provide a geometric repre...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566620/ https://www.ncbi.nlm.nih.gov/pubmed/23393618 http://dx.doi.org/10.1038/srep01236 |
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author | Lum, P. Y. Singh, G. Lehman, A. Ishkanov, T. Vejdemo-Johansson, M. Alagappan, M. Carlsson, J. Carlsson, G. |
author_facet | Lum, P. Y. Singh, G. Lehman, A. Ishkanov, T. Vejdemo-Johansson, M. Alagappan, M. Carlsson, J. Carlsson, G. |
author_sort | Lum, P. Y. |
collection | PubMed |
description | This paper applies topological methods to study complex high dimensional data sets by extracting shapes (patterns) and obtaining insights about them. Our method combines the best features of existing standard methodologies such as principal component and cluster analyses to provide a geometric representation of complex data sets. Through this hybrid method, we often find subgroups in data sets that traditional methodologies fail to find. Our method also permits the analysis of individual data sets as well as the analysis of relationships between related data sets. We illustrate the use of our method by applying it to three very different kinds of data, namely gene expression from breast tumors, voting data from the United States House of Representatives and player performance data from the NBA, in each case finding stratifications of the data which are more refined than those produced by standard methods. |
format | Online Article Text |
id | pubmed-3566620 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-35666202013-02-07 Extracting insights from the shape of complex data using topology Lum, P. Y. Singh, G. Lehman, A. Ishkanov, T. Vejdemo-Johansson, M. Alagappan, M. Carlsson, J. Carlsson, G. Sci Rep Article This paper applies topological methods to study complex high dimensional data sets by extracting shapes (patterns) and obtaining insights about them. Our method combines the best features of existing standard methodologies such as principal component and cluster analyses to provide a geometric representation of complex data sets. Through this hybrid method, we often find subgroups in data sets that traditional methodologies fail to find. Our method also permits the analysis of individual data sets as well as the analysis of relationships between related data sets. We illustrate the use of our method by applying it to three very different kinds of data, namely gene expression from breast tumors, voting data from the United States House of Representatives and player performance data from the NBA, in each case finding stratifications of the data which are more refined than those produced by standard methods. Nature Publishing Group 2013-02-07 /pmc/articles/PMC3566620/ /pubmed/23393618 http://dx.doi.org/10.1038/srep01236 Text en Copyright © 2013, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by-nc-nd/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-nd/3.0/ |
spellingShingle | Article Lum, P. Y. Singh, G. Lehman, A. Ishkanov, T. Vejdemo-Johansson, M. Alagappan, M. Carlsson, J. Carlsson, G. Extracting insights from the shape of complex data using topology |
title | Extracting insights from the shape of complex data using topology |
title_full | Extracting insights from the shape of complex data using topology |
title_fullStr | Extracting insights from the shape of complex data using topology |
title_full_unstemmed | Extracting insights from the shape of complex data using topology |
title_short | Extracting insights from the shape of complex data using topology |
title_sort | extracting insights from the shape of complex data using topology |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566620/ https://www.ncbi.nlm.nih.gov/pubmed/23393618 http://dx.doi.org/10.1038/srep01236 |
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