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Alternaric acid: formal synthesis and related studies
A silyl glyoxylate three-component-coupling methodology has been exploited to achieve a formal synthesis, an analogue to an intermediate in a distinct formal synthetic route, and a third (unique) approach to the natural product alternaric acid. Highlighted in this study is the versatility of silyl g...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566800/ https://www.ncbi.nlm.nih.gov/pubmed/23399952 http://dx.doi.org/10.3762/bjoc.9.19 |
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author | Slade, Michael C Johnson, Jeffrey S |
author_facet | Slade, Michael C Johnson, Jeffrey S |
author_sort | Slade, Michael C |
collection | PubMed |
description | A silyl glyoxylate three-component-coupling methodology has been exploited to achieve a formal synthesis, an analogue to an intermediate in a distinct formal synthetic route, and a third (unique) approach to the natural product alternaric acid. Highlighted in this study is the versatility of silyl glyoxylates to engage a variety of nucleophile and electrophile pairs to provide wide latitude in the approach to complex molecule synthesis. |
format | Online Article Text |
id | pubmed-3566800 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Beilstein-Institut |
record_format | MEDLINE/PubMed |
spelling | pubmed-35668002013-02-11 Alternaric acid: formal synthesis and related studies Slade, Michael C Johnson, Jeffrey S Beilstein J Org Chem Full Research Paper A silyl glyoxylate three-component-coupling methodology has been exploited to achieve a formal synthesis, an analogue to an intermediate in a distinct formal synthetic route, and a third (unique) approach to the natural product alternaric acid. Highlighted in this study is the versatility of silyl glyoxylates to engage a variety of nucleophile and electrophile pairs to provide wide latitude in the approach to complex molecule synthesis. Beilstein-Institut 2013-01-24 /pmc/articles/PMC3566800/ /pubmed/23399952 http://dx.doi.org/10.3762/bjoc.9.19 Text en Copyright © 2013, Slade and Johnson https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
spellingShingle | Full Research Paper Slade, Michael C Johnson, Jeffrey S Alternaric acid: formal synthesis and related studies |
title | Alternaric acid: formal synthesis and related studies |
title_full | Alternaric acid: formal synthesis and related studies |
title_fullStr | Alternaric acid: formal synthesis and related studies |
title_full_unstemmed | Alternaric acid: formal synthesis and related studies |
title_short | Alternaric acid: formal synthesis and related studies |
title_sort | alternaric acid: formal synthesis and related studies |
topic | Full Research Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566800/ https://www.ncbi.nlm.nih.gov/pubmed/23399952 http://dx.doi.org/10.3762/bjoc.9.19 |
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