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Alternaric acid: formal synthesis and related studies

A silyl glyoxylate three-component-coupling methodology has been exploited to achieve a formal synthesis, an analogue to an intermediate in a distinct formal synthetic route, and a third (unique) approach to the natural product alternaric acid. Highlighted in this study is the versatility of silyl g...

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Detalles Bibliográficos
Autores principales: Slade, Michael C, Johnson, Jeffrey S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566800/
https://www.ncbi.nlm.nih.gov/pubmed/23399952
http://dx.doi.org/10.3762/bjoc.9.19
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author Slade, Michael C
Johnson, Jeffrey S
author_facet Slade, Michael C
Johnson, Jeffrey S
author_sort Slade, Michael C
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description A silyl glyoxylate three-component-coupling methodology has been exploited to achieve a formal synthesis, an analogue to an intermediate in a distinct formal synthetic route, and a third (unique) approach to the natural product alternaric acid. Highlighted in this study is the versatility of silyl glyoxylates to engage a variety of nucleophile and electrophile pairs to provide wide latitude in the approach to complex molecule synthesis.
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spelling pubmed-35668002013-02-11 Alternaric acid: formal synthesis and related studies Slade, Michael C Johnson, Jeffrey S Beilstein J Org Chem Full Research Paper A silyl glyoxylate three-component-coupling methodology has been exploited to achieve a formal synthesis, an analogue to an intermediate in a distinct formal synthetic route, and a third (unique) approach to the natural product alternaric acid. Highlighted in this study is the versatility of silyl glyoxylates to engage a variety of nucleophile and electrophile pairs to provide wide latitude in the approach to complex molecule synthesis. Beilstein-Institut 2013-01-24 /pmc/articles/PMC3566800/ /pubmed/23399952 http://dx.doi.org/10.3762/bjoc.9.19 Text en Copyright © 2013, Slade and Johnson https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Slade, Michael C
Johnson, Jeffrey S
Alternaric acid: formal synthesis and related studies
title Alternaric acid: formal synthesis and related studies
title_full Alternaric acid: formal synthesis and related studies
title_fullStr Alternaric acid: formal synthesis and related studies
title_full_unstemmed Alternaric acid: formal synthesis and related studies
title_short Alternaric acid: formal synthesis and related studies
title_sort alternaric acid: formal synthesis and related studies
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566800/
https://www.ncbi.nlm.nih.gov/pubmed/23399952
http://dx.doi.org/10.3762/bjoc.9.19
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