Dp44mT targets the AKT, TGF-β and ERK pathways via the metastasis suppressor NDRG1 in normal prostate epithelial cells and prostate cancer cells

BACKGROUND: Effective treatment of prostate cancer should be based on targeting interactions between tumour cell signalling pathways and key converging downstream effectors. Here, we determined how the tumourigenic phosphoinositide 3-kinase/protein kinase B (PI3K/AKT), tumour-suppressive phosphatase...

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Detalles Bibliográficos
Autores principales: Dixon, K M, Lui, G Y L, Kovacevic, Z, Zhang, D, Yao, M, Chen, Z, Dong, Q, Assinder, S J, Richardson, D R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566801/
https://www.ncbi.nlm.nih.gov/pubmed/23287991
http://dx.doi.org/10.1038/bjc.2012.582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566801/
https://www.ncbi.nlm.nih.gov/pubmed/23287991
http://dx.doi.org/10.1038/bjc.2012.582

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