Cargando…

REG Iα is a biomarker for predicting response to chemotherapy with S-1 plus cisplatin in patients with unresectable stage IV gastric cancer

BACKGROUND: The regenerating gene Iα (REG Iα) is involved in gastric carcinogenesis as an antiapoptotic factor. Therefore, we investigated whether REG Iα confers resistance to chemotherapeutic drugs in gastric cancer (GC) cells and whether REG Iα expression is useful for predicting the response to c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sekikawa, A, Fukui, H, Zhang, X, Maruo, T, Tsumura, T, Okabe, Y, Wakasa, T, Osaki, Y, Chiba, T, Tomita, T, Oshima, T, Watari, J, Miwa, H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566803/ https://www.ncbi.nlm.nih.gov/pubmed/23322208 http://dx.doi.org/10.1038/bjc.2012.572

Ejemplares similares

IL-22 produced by cancer-associated fibroblasts promotes gastric cancer cell invasion via STAT3 and ERK signaling
por: Fukui, H, et al.
Publicado: (2014)

Expression of SDF-1α and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer
por: Yoshitake, N, et al.
Publicado: (2008)

The Link between Type III Reg and STAT3-Associated Cytokines in Inflamed Colonic Tissues
por: Xu, Xin, et al.
Publicado: (2019)

CYP2A6 and ERCC1 polymorphisms correlate with efficacy of S-1 plus cisplatin in metastatic gastric cancer patients
por: Park, S R, et al.
Publicado: (2011)

A Case of Myelodysplastic Syndrome with Intestinal Behçet’s Disease-Like Symptoms Treated by Prednisolone and Azacitidine
por: Endo, Masatsugu, et al.
Publicado: (2015)

Thymidine synthase, thymidine phosphorylase, and excision repair cross-complementation group 1 expression as predictive markers of capecitabine plus cisplatin chemotherapy as first-line treatment for patients with advanced oesophageal squamous cell carcinoma
por: Lee, S, et al.
Publicado: (2010)

CTL- vs T(reg) lymphocyte-attracting chemokines, CCL4 and CCL20, are strong reciprocal predictive markers for survival of patients with oesophageal squamous cell carcinoma
por: Liu, J Y, et al.
Publicado: (2015)

Role of the β-Catenin/REG Iα Axis in the Proliferation of Sessile Serrated Adenoma/Polyps Associated with Fusobacterium nucleatum
por: Nishimura, Heihachiro, et al.
Publicado: (2021)

Human equilibrative nucleoside transporter 1 and Notch3 can predict gemcitabine effects in patients with unresectable pancreatic cancer
por: Eto, K, et al.
Publicado: (2013)

Cisplatin plus paclitaxel and maintenance of bevacizumab on tumour progression, dissemination, and survival of ovarian carcinoma xenograft models
por: Oliva, P, et al.
Publicado: (2012)

ERCC1 expression as a predictive marker of squamous cell carcinoma of the head and neck treated with cisplatin-based concurrent chemoradiation
por: Jun, H J, et al.
Publicado: (2008)

Immunostaining of thymidylate synthase and p53 for predicting chemoresistance to S-1/cisplatin in gastric cancer
por: Kamoshida, S, et al.
Publicado: (2007)

Conversion surgery following gemcitabine plus cisplatin therapy for initially unresectable gallbladder cancer with peritoneal carcinomatosis: a case report
por: Wakasa, Yusuke, et al.
Publicado: (2022)

Nicotine increases the resistance of lung cancer cells to cisplatin through enhancing Bcl-2 stability
por: Nishioka, T, et al.
Publicado: (2014)

Esophageal Sensation and Esophageal Hypersensitivity - Overview From Bench to Bedside
por: Miwa, Hiroto, et al.
Publicado: (2010)

Association between gastrointestinal motility and macrophage/mast cell distribution in mice during the healing stage after DSS-induced colitis
por: Kodani, Mio, et al.
Publicado: (2018)

Preventing Metachronous Gastric Cancer after the Endoscopic Resection of Gastric Epithelial Neoplasia: Roles of Helicobacter pylori Eradication and Aspirin
por: Watari, Jiro, et al.
Publicado: (2020)

Role of HER3 expression and PTEN loss in patients with HER2-overexpressing metastatic breast cancer (MBC) who received taxane plus trastuzumab treatment
por: Park, Y H, et al.
Publicado: (2014)

Inhibition of TGF-β and EGF pathway gene expression and migration of oral carcinoma cells by mucosa-associated lymphoid tissue 1
por: Ohyama, Y, et al.
Publicado: (2013)

Recent understanding of the pathophysiology of functional dyspepsia: role of the duodenum as the pathogenic center
por: Miwa, Hiroto, et al.
Publicado: (2019)

Alteration of GLP-1/GPR43 expression and gastrointestinal motility in dysbiotic mice treated with vancomycin
por: Xu, Xin, et al.
Publicado: (2019)

Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis
por: Zheng, H-C, et al.
Publicado: (2006)

Therapeutic outcomes and prognostic factors in unresectable gallbladder cancer treated with gemcitabine plus cisplatin
por: You, Min su, et al.
Publicado: (2019)

MiR-224 promotes the chemoresistance of human lung adenocarcinoma cells to cisplatin via regulating G(1)/S transition and apoptosis by targeting p21(WAF1/CIP1)
por: Wang, H, et al.
Publicado: (2014)

Single extreme low dose/low dose rate irradiation causes alteration in lifespan and genome instability in primary human cells
por: Okada, M, et al.
Publicado: (2007)

Cisplatin-induced expression of Gb3 enables verotoxin-1 treatment of cisplatin resistance in malignant pleural mesothelioma cells
por: Johansson, D, et al.
Publicado: (2010)

Dexamethasone-induced cisplatin and gemcitabine resistance in lung carcinoma samples treated ex vivo
por: Gassler, N, et al.
Publicado: (2005)

Successful Self-Expandable Metallic Stent Placement for a Case of Distal Rectal Stenosis due to Gastric Cancer Metastasis
por: Okugawa, Takuya, et al.
Publicado: (2013)

Colonic M1 macrophage is associated with the prolongation of gastrointestinal motility and obesity in mice treated with vancomycin
por: Inoue, Yoshihito, et al.
Publicado: (2019)

Phosphorylated STAT3 expression linked to SOCS3 methylation is associated with proliferative ability of gastric mucosa in patients with early gastric cancer
por: Fukui, Hirokazu, et al.
Publicado: (2020)

Enhancement of the activity of phenoxodiol by cisplatin in prostate cancer cells
por: McPherson, R A C, et al.
Publicado: (2009)

Proteomic analysis of stage I primary lung adenocarcinoma aimed at individualisation of postoperative therapy
por: Maeda, J, et al.
Publicado: (2008)

Combination chemotherapy with epirubicin, docetaxel and cisplatin (EDP) in metastatic or recurrent, unresectable gastric cancer
por: Lee, S-H, et al.
Publicado: (2004)

Maspin is a marker for early recurrence in primary stage III and IV colorectal cancer
por: Snoeren, N, et al.
Publicado: (2013)

The Potential Role of REG Family Proteins in Inflammatory and Inflammation-Associated Diseases of the Gastrointestinal Tract
por: Sun, Chao, et al.
Publicado: (2021)

CDX2 and Reg IV expression and correlation in gastric cancer
por: Chai, Dandan, et al.
Publicado: (2021)

DNA methylation silencing of microRNA gene methylator in the precancerous background mucosa with and without gastric cancer: Analysis of the effects of H. pylori eradication and long-term aspirin use
por: Watari, Jiro, et al.
Publicado: (2019)

Significance of E-cadherin expression in triple-negative breast cancer
por: Kashiwagi, S, et al.
Publicado: (2010)

Dose-finding study of irinotecan and cisplatin plus concurrent radiotherapy for unresectable stage III non-small-cell lung cancer [seecomments]
por: Yokoyama, A., et al.
Publicado: (1998)

Prognostic value of histological type in stage IV ovarian carcinoma: a retrospective analysis of 223 patients
por: Mizuno, M, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_vdmbp1qsv76geev9uf2jc5sphv