An inherited NBN mutation is associated with poor prognosis prostate cancer

BACKGROUND: To establish the contribution of eight founder alleles in three DNA damage repair genes (BRCA1, CHEK2 and NBS1) to prostate cancer in Poland, and to measure the impact of these variants on survival among patients. METHODS: Three thousand seven hundred fifty men with prostate cancer and 3...

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Detalles Bibliográficos
Autores principales: Cybulski, C, Wokołorczyk, D, Kluźniak, W, Jakubowska, A, Górski, B, Gronwald, J, Huzarski, T, Kashyap, A, Byrski, T, Dębniak, T, Gołąb, A, Gliniewicz, B, Sikorski, A, Świtała, J, Borkowski, T, Borkowski, A, Antczak, A, Wojnar, Ł, Przybyła, J, Sosnowski, M, Małkiewicz, B, Zdrojowy, R, Sikorska-Radek, P, Matych, J, Wilkosz, J, Różański, W, Kiś, J, Bar, K, Bryniarski, P, Paradysz, A, Jersak, K, Niemirowicz, J, Słupski, P, Jarzemski, P, Skrzypczyk, M, Dobruch, J, Domagała, P, Narod, S A, Lubiński, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Genetics & Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566821/
https://www.ncbi.nlm.nih.gov/pubmed/23149842
http://dx.doi.org/10.1038/bjc.2012.486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566821/
https://www.ncbi.nlm.nih.gov/pubmed/23149842
http://dx.doi.org/10.1038/bjc.2012.486

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