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An inherited NBN mutation is associated with poor prognosis prostate cancer
BACKGROUND: To establish the contribution of eight founder alleles in three DNA damage repair genes (BRCA1, CHEK2 and NBS1) to prostate cancer in Poland, and to measure the impact of these variants on survival among patients. METHODS: Three thousand seven hundred fifty men with prostate cancer and 3...
Autores principales: | Cybulski, C, Wokołorczyk, D, Kluźniak, W, Jakubowska, A, Górski, B, Gronwald, J, Huzarski, T, Kashyap, A, Byrski, T, Dębniak, T, Gołąb, A, Gliniewicz, B, Sikorski, A, Świtała, J, Borkowski, T, Borkowski, A, Antczak, A, Wojnar, Ł, Przybyła, J, Sosnowski, M, Małkiewicz, B, Zdrojowy, R, Sikorska-Radek, P, Matych, J, Wilkosz, J, Różański, W, Kiś, J, Bar, K, Bryniarski, P, Paradysz, A, Jersak, K, Niemirowicz, J, Słupski, P, Jarzemski, P, Skrzypczyk, M, Dobruch, J, Domagała, P, Narod, S A, Lubiński, J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566821/ https://www.ncbi.nlm.nih.gov/pubmed/23149842 http://dx.doi.org/10.1038/bjc.2012.486 |
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