Putative SF2 helicases of the early-branching eukaryote Giardia lamblia are involved in antigenic variation and parasite differentiation into cysts

BACKGROUND: Regulation of surface antigenic variation in Giardia lamblia is controlled post-transcriptionally by an RNA-interference (RNAi) pathway that includes a Dicer-like bidentate RNase III (gDicer). This enzyme, however, lacks the RNA helicase domain present in Dicer enzymes from higher eukary...

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Detalles Bibliográficos
Autores principales: Gargantini, Pablo R, Serradell, Marianela C, Torri, Alessandro, Lujan, Hugo D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566956/
https://www.ncbi.nlm.nih.gov/pubmed/23190735
http://dx.doi.org/10.1186/1471-2180-12-284

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