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Expansion in CD39(+) CD4(+) Immunoregulatory T Cells and Rarity of Th17 Cells in HTLV-1 Infected Patients Is Associated with Neurological Complications
HTLV-1 infection is associated with several inflammatory disorders, including the neurodegenerative condition HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). It is unclear why a minority of infected subjects develops HAM/TSP. CD4(+) T cells are the main target of infection and p...
Autores principales: | Leal, Fabio E., Ndhlovu, Lishomwa C., Hasenkrug, Aaron M., Bruno, Fernanda R., Carvalho, Karina I., Wynn-Williams, Harry, Neto, Walter K., Sanabani, Sabri S., Segurado, Aluisio C., Nixon, Douglas F., Kallas, Esper G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566991/ https://www.ncbi.nlm.nih.gov/pubmed/23409198 http://dx.doi.org/10.1371/journal.pntd.0002028 |
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