An Efficient Procedure for Marker-Free Mutagenesis of S. coelicolor by Site-Specific Recombination for Secondary Metabolite Overproduction

Streptomyces bacteria are known for producing important natural compounds by secondary metabolism, especially antibiotics with novel biological activities. Functional studies of antibiotic-biosynthesizing gene clusters are generally through homologous genomic recombination by gene-targeting vectors....

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Detalles Bibliográficos
Autores principales: Zhang, Bo, Zhang, Lin, Dai, Ruixue, Yu, Meiying, Zhao, Guoping, Ding, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567011/
https://www.ncbi.nlm.nih.gov/pubmed/23409083
http://dx.doi.org/10.1371/journal.pone.0055906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567011/
https://www.ncbi.nlm.nih.gov/pubmed/23409083
http://dx.doi.org/10.1371/journal.pone.0055906

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