Cargando…
Neurodegeneration in a Drosophila Model for the Function of TMCC2, an Amyloid Protein Precursor-Interacting and Apolipoprotein E-Binding Protein
We previously identified TMCC2 as a protein that interacted differentially with normal versus Alzheimer's disease-risk forms of both apolipoprotein E (apoE) and the amyloid protein precursor (APP). We hypothesized that disrupted function of TMCC2 would affect neurodegeneration. To test this hyp...
Autor principal: | Hopkins, Paul C. R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567013/ https://www.ncbi.nlm.nih.gov/pubmed/23409049 http://dx.doi.org/10.1371/journal.pone.0055810 |
Ejemplares similares
-
Amyloid precursor protein: more than just neurodegeneration
por: Pimplikar, Sanjay W, et al.
Publicado: (2011) -
Analysis of Amyloid Precursor Protein Function in Drosophila melanogaster
por: Cassar, Marlène, et al.
Publicado: (2016) -
Targeting apolipoprotein E and N-terminal amyloid β-protein precursor interaction improves cognition and reduces amyloid pathology in Alzheimer’s mice
por: Sawmiller, Darrell, et al.
Publicado: (2023) -
Cerebral apolipoprotein E and amyloid precursor-like protein 1 as risk factors for chronic neurodegeneration after non-traumatic acute brain injury (ABI)
por: Santacruz, Carlos A., et al.
Publicado: (2023) -
Ablation of Tmcc2 Gene Impairs Erythropoiesis in Mice
por: Kumari, Ranju, et al.
Publicado: (2022)