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Isolation of Human Monoclonal Antibodies to the Envelope E2 Protein of Hepatitis C Virus and Their Characterization
We isolated and characterized two human monoclonal antibodies to the envelope E2 protein of hepatitis C virus (HCV). Lymphoblastoid cell lines stably producing antibodies were obtained by immortalizing peripheral blood mononuclear cells of a patient with chronic hepatitis C using Epstein-Barr virus....
Autores principales: | Shimizu, Yohko K., Hijikata, Minako, Oshima, Masamichi, Shimizu, Kazufumi, Alter, Harvey J., Purcell, Robert H., Yoshikura, Hiroshi, Hotta, Hak |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567033/ https://www.ncbi.nlm.nih.gov/pubmed/23409074 http://dx.doi.org/10.1371/journal.pone.0055874 |
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