Complete Solubilization and Purification of Recombinant Human Growth Hormone Produced in Escherichia coli

High-level expression of recombinant human growth hormone (hGH) in Escherichia coli (E. coli) leads to the formation of insoluble aggregates as inclusion bodies devoid of biological activity. Until recently, significant efforts have been made to improve the recovery of active hGH from inclusion bodi...

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Detalles Bibliográficos
Autores principales: Kim, Min-Ji, Park, Hyun Soo, Seo, Kyung Hye, Yang, Hyo-Jin, Kim, Sook-Kyung, Choi, Jun-Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567055/
https://www.ncbi.nlm.nih.gov/pubmed/23409149
http://dx.doi.org/10.1371/journal.pone.0056168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567055/
https://www.ncbi.nlm.nih.gov/pubmed/23409149
http://dx.doi.org/10.1371/journal.pone.0056168

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