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Characterization of Fragile X Mental Retardation Protein Recruitment and Dynamics in Drosophila Stress Granules
The RNA-binding protein Fragile X Mental Retardation (FMRP) is an evolutionarily conserved protein that is particularly abundant in the brain due to its high expression in neurons. FMRP deficiency causes fragile X mental retardation syndrome. In neurons, FMRP controls the translation of target mRNAs...
Autores principales: | Gareau, Cristina, Houssin, Elise, Martel, David, Coudert, Laetitia, Mellaoui, Samia, Huot, Marc-Etienne, Laprise, Patrick, Mazroui, Rachid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567066/ https://www.ncbi.nlm.nih.gov/pubmed/23408971 http://dx.doi.org/10.1371/journal.pone.0055342 |
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