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Nebulized Fibrinolytic Agents Improve Pulmonary Fibrinolysis but Not Inflammation in Rat Models of Direct and Indirect Acute Lung Injury

BACKGROUND: Critically ill patients frequently develop acute lung injury (ALI). Disturbed alveolar fibrin turnover, a characteristic feature of ALI, is the result of both activation of coagulation and inhibition of fibrinolysis. Nebulized fibrinolytic agents could exert lung–protective effects, via...

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Detalles Bibliográficos
Autores principales:	Hofstra, Jorrit J., Cornet, Alexander D., Declerck, Paul J., Dixon, Barry, Aslami, Hamid, Vlaar, Alexander P. J., Roelofs, Joris J., van der Poll, Tom, Levi, Marcel, Schultz, Marcus J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567078/ https://www.ncbi.nlm.nih.gov/pubmed/23408962 http://dx.doi.org/10.1371/journal.pone.0055262

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