Altered Cohesin Gene Dosage Affects Mammalian Meiotic Chromosome Structure and Behavior

Based on studies in mice and humans, cohesin loss from chromosomes during the period of protracted meiotic arrest appears to play a major role in chromosome segregation errors during female meiosis. In mice, mutations in meiosis-specific cohesin genes cause meiotic disturbances and infertility. Howe...

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Detalles Bibliográficos
Autores principales: Murdoch, Brenda, Owen, Nichole, Stevense, Michelle, Smith, Helen, Nagaoka, So, Hassold, Terry, McKay, Michael, Xu, Huiling, Fu, Jun, Revenkova, Ekaterina, Jessberger, Rolf, Hunt, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567145/
https://www.ncbi.nlm.nih.gov/pubmed/23408896
http://dx.doi.org/10.1371/journal.pgen.1003241

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