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Mitotic Evolution of Plasmodium falciparum Shows a Stable Core Genome but Recombination in Antigen Families
Malaria parasites elude eradication attempts both within the human host and across nations. At the individual level, parasites evade the host immune responses through antigenic variation. At the global level, parasites escape drug pressure through single nucleotide variants and gene copy amplificati...
Autores principales: | Bopp, Selina E. R., Manary, Micah J., Bright, A. Taylor, Johnston, Geoffrey L., Dharia, Neekesh V., Luna, Fabio L., McCormack, Susan, Plouffe, David, McNamara, Case W., Walker, John R., Fidock, David A., Denchi, Eros Lazzerini, Winzeler, Elizabeth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567157/ https://www.ncbi.nlm.nih.gov/pubmed/23408914 http://dx.doi.org/10.1371/journal.pgen.1003293 |
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