Control of Multicellular Development by the Physically Interacting Deneddylases DEN1/DenA and COP9 Signalosome

Deneddylases remove the ubiquitin-like protein Nedd8 from modified proteins. An increased deneddylase activity has been associated with various human cancers. In contrast, we show here that a mutant strain of the model fungus Aspergillus nidulans deficient in two deneddylases is viable but can only...

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Detalles Bibliográficos
Autores principales: Christmann, Martin, Schmaler, Tilo, Gordon, Colin, Huang, Xiaohua, Bayram, Özgür, Schinke, Josua, Stumpf, Sina, Dubiel, Wolfgang, Braus, Gerhard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567183/
https://www.ncbi.nlm.nih.gov/pubmed/23408908
http://dx.doi.org/10.1371/journal.pgen.1003275

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