Polygenic Modeling with Bayesian Sparse Linear Mixed Models

Both linear mixed models (LMMs) and sparse regression models are widely used in genetics applications, including, recently, polygenic modeling in genome-wide association studies. These two approaches make very different assumptions, so are expected to perform well in different situations. However, i...

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Detalles Bibliográficos
Autores principales: Zhou, Xiang, Carbonetto, Peter, Stephens, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567190/
https://www.ncbi.nlm.nih.gov/pubmed/23408905
http://dx.doi.org/10.1371/journal.pgen.1003264

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