Tethered capsule endomicroscopy enables less-invasive imaging of gastrointestinal tract microstructure

Here, we introduce “tethered capsule endomicroscopy,” that involves swallowing an optomechanically-engineered pill that captures cross-sectional, 30 μm (lateral) × 7 μm (axial) resolution, microscopic images of the gut wall as it travels through the digestive tract. Results in human subjects show th...

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Autores principales: Gora, Michalina J., Sauk, Jenny S., Carruth, Robert W., Gallagher, Kevin A., Suter, Melissa J., Nishioka, Norman S., Kava, Lauren E., Rosenberg, Mireille, Bouma, Brett E., Tearney, Guillermo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567218/
https://www.ncbi.nlm.nih.gov/pubmed/23314056
http://dx.doi.org/10.1038/nm.3052
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author Gora, Michalina J.
Sauk, Jenny S.
Carruth, Robert W.
Gallagher, Kevin A.
Suter, Melissa J.
Nishioka, Norman S.
Kava, Lauren E.
Rosenberg, Mireille
Bouma, Brett E.
Tearney, Guillermo J.
author_facet Gora, Michalina J.
Sauk, Jenny S.
Carruth, Robert W.
Gallagher, Kevin A.
Suter, Melissa J.
Nishioka, Norman S.
Kava, Lauren E.
Rosenberg, Mireille
Bouma, Brett E.
Tearney, Guillermo J.
author_sort Gora, Michalina J.
collection PubMed
description Here, we introduce “tethered capsule endomicroscopy,” that involves swallowing an optomechanically-engineered pill that captures cross-sectional, 30 μm (lateral) × 7 μm (axial) resolution, microscopic images of the gut wall as it travels through the digestive tract. Results in human subjects show that this technique rapidly provides three-dimensional, microstructural images of the upper gastrointestinal tract in a simple and painless procedure, opening up new opportunities for screening for internal diseases.
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spelling pubmed-35672182013-08-01 Tethered capsule endomicroscopy enables less-invasive imaging of gastrointestinal tract microstructure Gora, Michalina J. Sauk, Jenny S. Carruth, Robert W. Gallagher, Kevin A. Suter, Melissa J. Nishioka, Norman S. Kava, Lauren E. Rosenberg, Mireille Bouma, Brett E. Tearney, Guillermo J. Nat Med Article Here, we introduce “tethered capsule endomicroscopy,” that involves swallowing an optomechanically-engineered pill that captures cross-sectional, 30 μm (lateral) × 7 μm (axial) resolution, microscopic images of the gut wall as it travels through the digestive tract. Results in human subjects show that this technique rapidly provides three-dimensional, microstructural images of the upper gastrointestinal tract in a simple and painless procedure, opening up new opportunities for screening for internal diseases. 2013-01-13 2013-02 /pmc/articles/PMC3567218/ /pubmed/23314056 http://dx.doi.org/10.1038/nm.3052 Text en Users may view, print, copy, download and text and data- mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use: http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Gora, Michalina J.
Sauk, Jenny S.
Carruth, Robert W.
Gallagher, Kevin A.
Suter, Melissa J.
Nishioka, Norman S.
Kava, Lauren E.
Rosenberg, Mireille
Bouma, Brett E.
Tearney, Guillermo J.
Tethered capsule endomicroscopy enables less-invasive imaging of gastrointestinal tract microstructure
title Tethered capsule endomicroscopy enables less-invasive imaging of gastrointestinal tract microstructure
title_full Tethered capsule endomicroscopy enables less-invasive imaging of gastrointestinal tract microstructure
title_fullStr Tethered capsule endomicroscopy enables less-invasive imaging of gastrointestinal tract microstructure
title_full_unstemmed Tethered capsule endomicroscopy enables less-invasive imaging of gastrointestinal tract microstructure
title_short Tethered capsule endomicroscopy enables less-invasive imaging of gastrointestinal tract microstructure
title_sort tethered capsule endomicroscopy enables less-invasive imaging of gastrointestinal tract microstructure
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567218/
https://www.ncbi.nlm.nih.gov/pubmed/23314056
http://dx.doi.org/10.1038/nm.3052
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