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Modulating vascular intimal hyperplasia using HSV-1 mutant requires activated MEK

Outcomes of cardiovascular procedures, such as angioplasty and stent or bypass grafting are limited by failure, predominantly caused by pathological smooth muscle cell (SMC) proliferation, known as intimal hyperplasia. Local delivery of a genetically engineered herpes simplex virus (HSV) is known to...

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Detalles Bibliográficos
Autores principales:	Skelly, C L, He, Q, Spiguel, L, McCormick, S, Weichselbaum, R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567261/ https://www.ncbi.nlm.nih.gov/pubmed/22418062 http://dx.doi.org/10.1038/gt.2012.26

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