Successful treatment of Miescher's cheilitis in Melkersson-Rosenthal syndrome with betamethasone injections and doxycycline

We report a case of a 19-year-old girl who presented with 5-year history of swelling of upper lip and fissured tongue treated with dapsone then oral steroids without any improvement. Clinical examination found peripheral facial nerve paralysis and Labial mucosa biopsy showed non-necrotizing giganto-...

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Autores principales: Oudrhiri, Lamia, Chiheb, Soumiya, Marnissi, Farida, Zamiati, Soumaya, Benchikhi, Hakima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567407/
https://www.ncbi.nlm.nih.gov/pubmed/23397029
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author Oudrhiri, Lamia
Chiheb, Soumiya
Marnissi, Farida
Zamiati, Soumaya
Benchikhi, Hakima
author_facet Oudrhiri, Lamia
Chiheb, Soumiya
Marnissi, Farida
Zamiati, Soumaya
Benchikhi, Hakima
author_sort Oudrhiri, Lamia
collection PubMed
description We report a case of a 19-year-old girl who presented with 5-year history of swelling of upper lip and fissured tongue treated with dapsone then oral steroids without any improvement. Clinical examination found peripheral facial nerve paralysis and Labial mucosa biopsy showed non-necrotizing giganto-epithelioid granuloma. Diagnosis of Melkersson-Rosenthal syndrome was retaind because of association of cheilitis, lingua plicata and facial paralysis. Given the failure of dapsone and oral steroid we suggested an association of betamethasone injection and doxycycline. Gradual and permanent reduction of the upper lip volume was observed. One year follow up objectified no reactivation of cheilitis.
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spelling pubmed-35674072013-02-08 Successful treatment of Miescher's cheilitis in Melkersson-Rosenthal syndrome with betamethasone injections and doxycycline Oudrhiri, Lamia Chiheb, Soumiya Marnissi, Farida Zamiati, Soumaya Benchikhi, Hakima Pan Afr Med J Case Report We report a case of a 19-year-old girl who presented with 5-year history of swelling of upper lip and fissured tongue treated with dapsone then oral steroids without any improvement. Clinical examination found peripheral facial nerve paralysis and Labial mucosa biopsy showed non-necrotizing giganto-epithelioid granuloma. Diagnosis of Melkersson-Rosenthal syndrome was retaind because of association of cheilitis, lingua plicata and facial paralysis. Given the failure of dapsone and oral steroid we suggested an association of betamethasone injection and doxycycline. Gradual and permanent reduction of the upper lip volume was observed. One year follow up objectified no reactivation of cheilitis. The African Field Epidemiology Network 2012-12-09 /pmc/articles/PMC3567407/ /pubmed/23397029 Text en © Lamia Oudrhiri et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Oudrhiri, Lamia
Chiheb, Soumiya
Marnissi, Farida
Zamiati, Soumaya
Benchikhi, Hakima
Successful treatment of Miescher's cheilitis in Melkersson-Rosenthal syndrome with betamethasone injections and doxycycline
title Successful treatment of Miescher's cheilitis in Melkersson-Rosenthal syndrome with betamethasone injections and doxycycline
title_full Successful treatment of Miescher's cheilitis in Melkersson-Rosenthal syndrome with betamethasone injections and doxycycline
title_fullStr Successful treatment of Miescher's cheilitis in Melkersson-Rosenthal syndrome with betamethasone injections and doxycycline
title_full_unstemmed Successful treatment of Miescher's cheilitis in Melkersson-Rosenthal syndrome with betamethasone injections and doxycycline
title_short Successful treatment of Miescher's cheilitis in Melkersson-Rosenthal syndrome with betamethasone injections and doxycycline
title_sort successful treatment of miescher's cheilitis in melkersson-rosenthal syndrome with betamethasone injections and doxycycline
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567407/
https://www.ncbi.nlm.nih.gov/pubmed/23397029
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