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Precision medicine: an approach to R&D for delivering superior medicines to patients

Pharmaceutical R&D productivity has declined over the last decade despite increasing investments. Recent trends, however, indicate a potential reversal of this trend fueled by a wave of new biologics, vaccines and highly selective NCEs directed against targets validated by human genetics, focus...

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Detalles Bibliográficos
Autores principales: Dolsten, Mikael, Søgaard, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3567426/
https://www.ncbi.nlm.nih.gov/pubmed/23369459
http://dx.doi.org/10.1186/2001-1326-1-7
Descripción
Sumario:Pharmaceutical R&D productivity has declined over the last decade despite increasing investments. Recent trends, however, indicate a potential reversal of this trend fueled by a wave of new biologics, vaccines and highly selective NCEs directed against targets validated by human genetics, focus on new disease areas including orphan and genetic diseases and more precise tailoring of medicines to their target populations.